The specialists’ concerns in the field of culture regarding the imported sciences and negligence or perhaps moral nihilism exposure of a considerable portion of the Islamic society to sins shows the importance of exploring the meaning and concept of sin in the religious literature (Quran) in comparison with the equivalent idiomatic concept of sin in sociology and obtaining the similarities and differences between them. To this end, using explanatory method to investigate the Quran’s verses, the synonyms of the word sin were identified and defined. After that, the definitions of the related concepts were extracted from authentic texts of sociology and it has been concluded that despite of some commonalities, the mentioned two environments have fundamental differences in respect to resources, approaches, precision and recall, and consensus in definition.