The development of cyberspace and its dominance over contemporary human life posed numerous challenges to humans in terms of ethical, security, psychological and economic considerations. This has led some organizations, institutions, social activists and sympathetic scholars around the world to devise and disseminate several guidelines and ethical tenets to cyberspace users in order to prevent these challenges. Within the same approach, the present study examined and analyzed the principle of honesty in the Holy Koran and the narrations of the infallible figures and with its adjustment with cyberspace concluded that due to its conceptual development, reliance of all moral virtues on that, being observant over human existence and also its application to the verses and narrations, the "principle of honesty" is an a priori principle governing other ethical principles that, without any attachments, creates a moral obligation for man beyond time, space and arena.